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Ouabain targets the Na(+)/K(+)-ATPase α(3) isoform to inhibit cancer cell proliferation and induce apoptosis

Ouabain has been used for the treatment of heart failure and atrial fibrillation. Its potential anticancer effect has also attracted great interest. The aim of the present study was to evaluate the anticancer effect of ouabain and investigate its molecular target. The effects of ouabain on the viabi...

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Detalles Bibliográficos
Autores principales: Xiao, Yijun, Meng, Chen, Lin, Jie, Huang, Chaoqun, Zhang, Xiuli, Long, Yanyu, Huang, Yide, Lin, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688790/
https://www.ncbi.nlm.nih.gov/pubmed/29163695
http://dx.doi.org/10.3892/ol.2017.7070