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Cancer cell-soluble factors reprogram mesenchymal stromal cells to slow cycling, chemoresistant cells with a more stem-like state

BACKGROUND: Mesenchymal stem cells (MSCs) play different roles in modulating tumor progression, growth, and metastasis. MSCs are recruited to the tumor site in large numbers and subsequently have an important microenvironmental role in modulating tumor progression and drug sensitivity. However, the...

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Detalles Bibliográficos
Autores principales: El-Badawy, Ahmed, Ghoneim, Mohamed A., Gabr, Mahmoud M., Salah, Radwa Ayman, Mohamed, Ihab K., Amer, Marwa, El-Badri, Nagwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688803/
https://www.ncbi.nlm.nih.gov/pubmed/29115987
http://dx.doi.org/10.1186/s13287-017-0709-9