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Crystal structure and fluorescence properties of the iSpinach aptamer in complex with DFHBI

Fluorogenic RNA aptamers are short nucleic acids able to specifically interact with small molecules and strongly enhance their fluorescence upon complex formation. Among the different systems recently introduced, Spinach, an aptamer forming a fluorescent complex with the 3,5-difluoro-4-hydroxybenzyl...

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Detalles Bibliográficos
Autores principales: Fernandez-Millan, Pablo, Autour, Alexis, Ennifar, Eric, Westhof, Eric, Ryckelynck, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689000/
https://www.ncbi.nlm.nih.gov/pubmed/28939697
http://dx.doi.org/10.1261/rna.063008.117