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Conservation of tRNA mimicry in the 5′-untranslated region of distinct HIV-1 subtypes
Human tRNA(Lys3) serves as the primer for reverse transcription in human immunodeficiency virus type-1 (HIV-1) and anneals to the complementary primer binding site (PBS) in the genome. All tRNA(Lys) isoacceptors interact with human lysyl-tRNA synthetase (hLysRS) and are selectively packaged into vir...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689005/ https://www.ncbi.nlm.nih.gov/pubmed/28860303 http://dx.doi.org/10.1261/rna.062182.117 |