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The 5′ region of Xist RNA has the potential to associate with chromatin through the A-repeat

X inactive-specific transcript (Xist) is a long noncoding RNA that plays an essential role in X chromosome inactivation. Although Xist RNA, like common protein-coding mRNAs, is transcribed by RNA polymerase II, spliced and polyadenylated, it is retained in the nucleus and associates with the X chrom...

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Detalles Bibliográficos
Autores principales: Chigi, Yuta, Sasaki, Hiroyuki, Sado, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689009/
https://www.ncbi.nlm.nih.gov/pubmed/28939698
http://dx.doi.org/10.1261/rna.062158.117