Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis

Human pregnancy is associated with enhanced de novo lipogenesis in the early stages followed by hyperlipidemia during advanced gestation. Liver X receptors (LXRs) are oxysterol-activated nuclear receptors that stimulate de novo lipogenesis and also promote the efflux of cholesterol from extrahepatic...

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Detalles Bibliográficos
Autores principales: Nikolova, Vanya, Papacleovoulou, Georgia, Bellafante, Elena, Borges Manna, Luiza, Jansen, Eugene, Baron, Silvère, Abu-Hayyeh, Shadi, Parker, Malcolm, Williamson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689017/
https://www.ncbi.nlm.nih.gov/pubmed/28420650
http://dx.doi.org/10.1152/ajpendo.00449.2016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689017/
https://www.ncbi.nlm.nih.gov/pubmed/28420650
http://dx.doi.org/10.1152/ajpendo.00449.2016

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