Effects of trimetazidine on mitochondrial respiratory function, biosynthesis, and fission/fusion in rats with acute myocardial ischemia

OBJECTIVE: Myocardial ischemia affects mitochondrial functions, leading to ionic imbalance and susceptibility to ventricular fibrillation. Trimetazidine, a metabolic agent, is clinically used in anti-anginal therapy. METHODS: In this study, the rats were orally treated by gavage with trimetazidine 1...

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Detalles Bibliográficos
Autores principales: Shi, Wen, Shangguan, Wenfeng, Zhang, Yue, Li, Can, Li, Guangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2017
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689048/
https://www.ncbi.nlm.nih.gov/pubmed/28761019
http://dx.doi.org/10.14744/AnatolJCardiol.2017.7771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689048/
https://www.ncbi.nlm.nih.gov/pubmed/28761019
http://dx.doi.org/10.14744/AnatolJCardiol.2017.7771

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