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Calcium-containing scaffolds induce bone regeneration by regulating mesenchymal stem cell differentiation and migration

BACKGROUND: Osteoinduction and subsequent bone formation rely on efficient mesenchymal stem cell (MSC) recruitment. It is also known that migration is induced by gradients of growth factors and cytokines. Degradation of Ca(2+)-containing biomaterials mimics the bone remodeling compartment producing...

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Detalles Bibliográficos
Autores principales: Aquino-Martínez, Rubén, Angelo, Alcira P., Pujol, Francesc Ventura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689169/
https://www.ncbi.nlm.nih.gov/pubmed/29145866
http://dx.doi.org/10.1186/s13287-017-0713-0