Are mice good models for human neuromuscular disease? Comparing muscle excursions in walking between mice and humans

BACKGROUND: The mouse is one of the most widely used animal models to study neuromuscular diseases and test new therapeutic strategies. However, findings from successful pre-clinical studies using mouse models frequently fail to translate to humans due to various factors. Differences in muscle funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Xiao, Charles, James P., Akay, Turgay, Hutchinson, John R., Blemker, Silvia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689180/
https://www.ncbi.nlm.nih.gov/pubmed/29145886
http://dx.doi.org/10.1186/s13395-017-0143-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689180/
https://www.ncbi.nlm.nih.gov/pubmed/29145886
http://dx.doi.org/10.1186/s13395-017-0143-9

Ejemplares similares