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TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion

BACKGROUND: Glioblastoma multiforme (GBM) is characterized by lethal aggressiveness and patients with GBM are in urgent need for new therapeutic avenues to improve quality of life. Current studies on tumor invasion focused on roles of cytokines in tumor microenvironment and numerous evidence suggest...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Zhang, Xin, Xu, Ran, Huang, Bin, Chen, An-Jing, Li, Chao, Wang, Jian, Li, Xin-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689187/
https://www.ncbi.nlm.nih.gov/pubmed/29145888
http://dx.doi.org/10.1186/s13046-017-0628-8