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Targeting protein quality control pathways in breast cancer

The efficient production, folding, and secretion of proteins is critical for cancer cell survival. However, cancer cells thrive under stress conditions that damage proteins, so many cancer cells overexpress molecular chaperones that facilitate protein folding and target misfolded proteins for degrad...

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Detalles Bibliográficos
Autores principales: Sannino, Sara, Brodsky, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689203/
https://www.ncbi.nlm.nih.gov/pubmed/29145850
http://dx.doi.org/10.1186/s12915-017-0449-4