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Targeting protein quality control pathways in breast cancer
The efficient production, folding, and secretion of proteins is critical for cancer cell survival. However, cancer cells thrive under stress conditions that damage proteins, so many cancer cells overexpress molecular chaperones that facilitate protein folding and target misfolded proteins for degrad...
Autores principales: | Sannino, Sara, Brodsky, Jeffrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689203/ https://www.ncbi.nlm.nih.gov/pubmed/29145850 http://dx.doi.org/10.1186/s12915-017-0449-4 |
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