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Structural effects of intra-articular TGF-β1 in moderate to advanced knee osteoarthritis: MRI-based assessment in a randomized controlled trial

BACKGROUND: To determine effects of allogeneic human chondrocytes expressing TGF-β1 (TG-C) on structural progression of MRI features of knee osteoarthritis over a 1 year period. METHODS: This phase II randomized controlled trial of TG-C included patients with moderate to advanced osteoarthritis. Pat...

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Detalles Bibliográficos
Autores principales: Guermazi, A., Kalsi, G., Niu, J., Crema, M. D., Copeland, R. O., Orlando, A., Noh, M. J., Roemer, F. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689208/
https://www.ncbi.nlm.nih.gov/pubmed/29145839
http://dx.doi.org/10.1186/s12891-017-1830-8