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Remote intracranial recurrence of IDH mutant gliomas is associated with TP53 mutations and an 8q gain

Most IDH mutant gliomas harbor either 1p/19q co-deletions or TP53 mutation; 1p/19q co-deleted tumors have significantly better prognoses than tumors harboring TP53 mutations. To investigate the clinical factors that contribute to differences in tumor progression of IDH mutant gliomas, we classified...

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Detalles Bibliográficos
Autores principales: Nakae, Shunsuke, Kato, Takema, Murayama, Kazuhiro, Sasaki, Hikaru, Abe, Masato, Kumon, Masanobu, Kumai, Tadashi, Yamashiro, Kei, Inamasu, Joji, Hasegawa, Mitsuhiro, Kurahashi, Hiroki, Hirose, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689569/
https://www.ncbi.nlm.nih.gov/pubmed/29156679
http://dx.doi.org/10.18632/oncotarget.20951