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A prenatal interruption of DISC1 function in the brain exhibits a lasting impact on adult behaviors, brain metabolism, and interneuron development

Mental illnesses like schizophrenia (SCZ) and major depression disorder (MDD) are devastating brain disorders. The SCZ risk gene, disrupted in schizophrenia 1 (DISC1), has been associated with neuropsychiatric conditions. However, little is known regarding the long-lasting impacts on brain metabolis...

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Detalles Bibliográficos
Autores principales: Deng, Dazhi, Jian, Chongdong, Lei, Ling, Zhou, Yijing, McSweeney, Colleen, Dong, Fengping, Shen, Yilun, Zou, Donghua, Wang, Yonggang, Wu, Yuan, Zhang, Limin, Mao, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689574/
https://www.ncbi.nlm.nih.gov/pubmed/29156684
http://dx.doi.org/10.18632/oncotarget.21381