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MiR-2964a-5p binding site SNP regulates ATM expression contributing to age-related cataract risk

This study was to explore the involvement of DNA repair genes in the pathogenesis of age-related cataract (ARC). We genotyped nine single nucleotide polymorphisms (SNPs) of genes responsible to DNA double strand breaks (DSBs) in 804 ARC cases and 804 controls in a cohort of eye diseases in Chinese p...

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Detalles Bibliográficos
Autores principales: Rong, Han, Gu, Shanshan, Zhang, Guowei, Kang, Lihua, Yang, Mei, Zhang, Junfang, Shen, Xinyue, Guan, Huaijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689585/
https://www.ncbi.nlm.nih.gov/pubmed/29156695
http://dx.doi.org/10.18632/oncotarget.17600