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Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR
MISIIR is a potential target for ovarian cancer (OC) therapy due to its tissue-specific pattern of expression. 3C23K is a novel therapeutic monoclonal anti-MISIIR antibody designed to recruit effector cells and promote cell death through ADCC (antibody dependent cell-mediated cytotoxicity). Our obje...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689604/ https://www.ncbi.nlm.nih.gov/pubmed/29156714 http://dx.doi.org/10.18632/oncotarget.19620 |