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Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR

MISIIR is a potential target for ovarian cancer (OC) therapy due to its tissue-specific pattern of expression. 3C23K is a novel therapeutic monoclonal anti-MISIIR antibody designed to recruit effector cells and promote cell death through ADCC (antibody dependent cell-mediated cytotoxicity). Our obje...

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Detalles Bibliográficos
Autores principales:	Gill, Sarah E., Zhang, Qing, Keeney, Gary L., Cliby, William A., Weroha, S. John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689604/ https://www.ncbi.nlm.nih.gov/pubmed/29156714 http://dx.doi.org/10.18632/oncotarget.19620

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