Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth

Obesity is a significant risk factor for pancreatic cancer, harboring a chronic inflammatory condition characterized by dysregulation of the adipokines, leptin and adiponectin, that in turn alter oncogenic signaling pathways. We and others have shown that leptin promotes the proliferation and an inv...

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Detalles Bibliográficos
Autores principales: Messaggio, Fanuel, Mendonsa, Alisha M., Castellanos, Jason, Nagathihalli, Nagaraj S., Gorden, Lee, Merchant, Nipun B., VanSaun, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689616/
https://www.ncbi.nlm.nih.gov/pubmed/29156726
http://dx.doi.org/10.18632/oncotarget.19905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689616/
https://www.ncbi.nlm.nih.gov/pubmed/29156726
http://dx.doi.org/10.18632/oncotarget.19905

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