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A RasGAP, DAB2IP, regulates lipid droplet homeostasis by serving as GAP toward RAB40C

Lipid droplet (LD) homeostasis involves activities of various RAB small GTPases. Recently, we found RAB40C was one of the RAB proteins regulating LD homeostasis. RAB40C contains a unique SOCS domain that is required for clustering of LDs. However, its precise functional role in LD homeostasis and me...

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Detalles Bibliográficos
Autores principales: Luo, Xiaomin, Li, Chunman, Tan, Ran, Xu, Xiaohui, Wu, William K.K., Satoh, Ayano, Wang, Tuanlao, Yu, Sidney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689619/
https://www.ncbi.nlm.nih.gov/pubmed/29156729
http://dx.doi.org/10.18632/oncotarget.19960