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Generation of patient specific human neural stem cells from Niemann-Pick disease type C patient-derived fibroblasts

Niemann-Pick disease type C (NPC) is a neurodegenerative and lysosomal lipid storage disorder, characterized by the abnormal accumulation of unesterified cholesterol and glycolipids, which is caused by mutations in the NPC1 genes. Here, we report the generation of human induced neural stem cells fro...

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Detalles Bibliográficos
Autores principales: Sung, Eun-Ah, Yu, Kyung-Rok, Shin, Ji-Hee, Seo, Yoojin, Kim, Hyung-Sik, Koog, Myung Guen, Kang, Insung, Kim, Jae-Jun, Lee, Byung-Chul, Shin, Tae-Hoon, Lee, Jin Young, Lee, Seunghee, Kang, Tae-Wook, Choi, Soon Won, Kang, Kyung-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689620/
https://www.ncbi.nlm.nih.gov/pubmed/29156730
http://dx.doi.org/10.18632/oncotarget.19976