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TSSC3 represses self-renewal of osteosarcoma stem cells and Nanog expression by inhibiting the Src/Akt pathway

Osteosarcoma is the most common type of bone cancer, and the second leading cause of cancer-related death in children and young adults. Osteosarcoma stem cells are essential for osteosarcoma initiation, metastasis, chemoresistance and recurrence. In the present study, we report that: 1) higher TSSC3...

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Detalles Bibliográficos
Autores principales: Yan, Guang-Ning, Tang, Xue-Feng, Zhang, Xian-Chao, He, Ting, Huang, Yu-Sheng, Zhang, Xi, Meng, Gang, Guo, De-Yu, Lv, Yang-Fan, Guo, Qiao-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689636/
https://www.ncbi.nlm.nih.gov/pubmed/29156746
http://dx.doi.org/10.18632/oncotarget.20429