MiR-221-regulated KIT level by wild type or leukemia mutant RUNX1: a determinant of single myeloblast fate decisions that – collectively – drives or hinders granulopoiesis

RUNX1, a master transcription factor of hematopoiesis, was shown to orchestrate both cell proliferation and differentiation during granulopoiesis by regulating microRNAs (miRs). In this study, taking advantage of the miR-ON reporter system, we monitored first, how the granulocyte colony stimulation...

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Detalles Bibliográficos
Autores principales: Rossetti, Stefano, Anauo, Michael J., Sacchi, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689646/
https://www.ncbi.nlm.nih.gov/pubmed/29156756
http://dx.doi.org/10.18632/oncotarget.21266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689646/
https://www.ncbi.nlm.nih.gov/pubmed/29156756
http://dx.doi.org/10.18632/oncotarget.21266

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