Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation

Multiple Myeloma (MM) is an incurable hematological malignancy affecting millions of people worldwide. As in all tumor cells both glucose and more recently glutamine have been identified as important for MM cellular metabolism, however there is some dispute as to the role of glutamine in MM cell sur...

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Detalles Bibliográficos
Autores principales: Effenberger, Madlen, Bommert, Kathryn S., Kunz, Viktoria, Kruk, Jessica, Leich, Ellen, Rudelius, Martina, Bargou, Ralf, Bommert, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689652/
https://www.ncbi.nlm.nih.gov/pubmed/29156762
http://dx.doi.org/10.18632/oncotarget.20691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689652/
https://www.ncbi.nlm.nih.gov/pubmed/29156762
http://dx.doi.org/10.18632/oncotarget.20691

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