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Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation
Multiple Myeloma (MM) is an incurable hematological malignancy affecting millions of people worldwide. As in all tumor cells both glucose and more recently glutamine have been identified as important for MM cellular metabolism, however there is some dispute as to the role of glutamine in MM cell sur...
Autores principales: | Effenberger, Madlen, Bommert, Kathryn S., Kunz, Viktoria, Kruk, Jessica, Leich, Ellen, Rudelius, Martina, Bargou, Ralf, Bommert, Kurt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689652/ https://www.ncbi.nlm.nih.gov/pubmed/29156762 http://dx.doi.org/10.18632/oncotarget.20691 |
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