STAT3 and STAT5A are potential therapeutic targets in castration-resistant prostate cancer

Mechanisms of castration-resistant prostate cancer (CRPC) are not well understood, thus hindering rational-based drug design. Activation of STAT3/5A, key components of the JAK/STAT pathway, is implicated in aggressive PC, yet their clinical relevance in CRPC remains elusive. Here, we evaluated the p...

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Detalles Bibliográficos
Autores principales: Mohanty, Sambit K., Yagiz, Kader, Pradhan, Dinesh, Luthringer, Daniel J., Amin, Mahul B., Alkan, Serhan, Cinar, Bekir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689662/
https://www.ncbi.nlm.nih.gov/pubmed/29156772
http://dx.doi.org/10.18632/oncotarget.20844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689662/
https://www.ncbi.nlm.nih.gov/pubmed/29156772
http://dx.doi.org/10.18632/oncotarget.20844

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