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Kaempferol induces autophagic cell death of hepatocellular carcinoma cells via activating AMPK signaling

In the present study, we demonstrate that Kaempferol inhibited survival and proliferation of established human hepatocellular carcinoma (HCC) cell lines (HepG2, Huh-7, BEL7402, and SMMC) and primary human HCC cells. Kaempferol treatment in HCC cells induced profound AMP-activated protein kinase (AMP...

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Detalles Bibliográficos
Autores principales: Han, Bing, Yu, Yi-Qun, Yang, Qi-Lian, Shen, Chun-Ying, Wang, Xiao-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689680/
https://www.ncbi.nlm.nih.gov/pubmed/29156790
http://dx.doi.org/10.18632/oncotarget.21043