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Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR

Non-invasive molecular analysis of circulating tumor DNA (ctDNA) is a promising application in personalized cancer management, although there is still much to learn about the biological characteristics of ctDNA. The present study compared absolute amounts of KRAS mutated ctDNA and total circulating...

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Detalles Bibliográficos
Autores principales: Kloten, Vera, Rüchel, Nadine, Brüchle, Nadina Ortiz, Gasthaus, Janina, Freudenmacher, Nils, Steib, Florian, Mijnes, Jolein, Eschenbruch, Julian, Binnebösel, Marcel, Knüchel, Ruth, Dahl, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689682/
https://www.ncbi.nlm.nih.gov/pubmed/29156792
http://dx.doi.org/10.18632/oncotarget.21134