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Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR
Non-invasive molecular analysis of circulating tumor DNA (ctDNA) is a promising application in personalized cancer management, although there is still much to learn about the biological characteristics of ctDNA. The present study compared absolute amounts of KRAS mutated ctDNA and total circulating...
Autores principales: | Kloten, Vera, Rüchel, Nadine, Brüchle, Nadina Ortiz, Gasthaus, Janina, Freudenmacher, Nils, Steib, Florian, Mijnes, Jolein, Eschenbruch, Julian, Binnebösel, Marcel, Knüchel, Ruth, Dahl, Edgar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689682/ https://www.ncbi.nlm.nih.gov/pubmed/29156792 http://dx.doi.org/10.18632/oncotarget.21134 |
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