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TET1 inhibits cell proliferation by inducing RASSF5 expression

Tet methylcytosine dioxygenases (TETs) catalyze the oxidative reactions of 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). However, TET1 roles in ovarian cancer cell growth are unknown. Here, we show that ectopic expression of TET1 increased 5hmC levels, and inhibited proliferation and colony fo...

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Detalles Bibliográficos
Autores principales: Li, Bo-Tai, Yu, Chao, Xu, Ying, Liu, Sheng-Bing, Fan, Heng-Yu, Pan, Wei-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689693/
https://www.ncbi.nlm.nih.gov/pubmed/29156803
http://dx.doi.org/10.18632/oncotarget.21189