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The effect of aspirin on circulating netrin-1 levels in humans is dependent on the inflammatory status of the vascular endothelium

In atherosclerotic animal models, the cyclo-oxygenase (COX)-inhibitor aspirin counteracts downregulation of endothelial-derived netrin-1, thus reducing arterial inflammation. We here explored the effect of aspirin on netrin-1 in healthy subjects undergoing influenza immunisation, which is an establi...

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Detalles Bibliográficos
Autores principales: Layne, Kerry, Goodman, Timothy, Ferro, Albert, Passacquale, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689705/
https://www.ncbi.nlm.nih.gov/pubmed/29156815
http://dx.doi.org/10.18632/oncotarget.21240