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The effect of aspirin on circulating netrin-1 levels in humans is dependent on the inflammatory status of the vascular endothelium
In atherosclerotic animal models, the cyclo-oxygenase (COX)-inhibitor aspirin counteracts downregulation of endothelial-derived netrin-1, thus reducing arterial inflammation. We here explored the effect of aspirin on netrin-1 in healthy subjects undergoing influenza immunisation, which is an establi...
Autores principales: | Layne, Kerry, Goodman, Timothy, Ferro, Albert, Passacquale, Gabriella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689705/ https://www.ncbi.nlm.nih.gov/pubmed/29156815 http://dx.doi.org/10.18632/oncotarget.21240 |
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