MDM4 genetic variants predict HPV16-positive tumors of patients with squamous cell carcinoma of the oropharynx

The increasing incidence of squamous cell carcinoma of the oropharynx (SCCOP) is majorly attributed to the human papillomavirus (HPV) infection. Both HPV and MDM4 play a critical role in inhibition of p53 activity, thus affecting HPV tumor status of SCCOP. Three polymorphisms in MDM4 were genotyped...

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Detalles Bibliográficos
Autores principales: Lu, Zhongming, Zhang, Hua, Tao, Ye, Li, Xiangping, Li, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689719/
https://www.ncbi.nlm.nih.gov/pubmed/29156829
http://dx.doi.org/10.18632/oncotarget.21414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689719/
https://www.ncbi.nlm.nih.gov/pubmed/29156829
http://dx.doi.org/10.18632/oncotarget.21414

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