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Protective effect of NSA on intestinal epithelial cells in a necroptosis model

OBJECTIVE: This study aimed to investigate the protective effect of the necroptosis inhibitor necrosulfonamide (NSA) on intestinal epithelial cells using a novel in vitro necroptosis model that mimics inflammatory bowel disease (IBD). METHODS: 2,4,6-trinitrobenzenesulfonic acid (TNBS) was perfused i...

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Detalles Bibliográficos
Autores principales: Dong, Wei, Zhang, Min, Zhu, Yaxi, Chen, Yuanhan, Zhao, Xingchen, Li, Ruizhao, Zhang, Li, Ye, Zhiming, Liang, Xingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689721/
https://www.ncbi.nlm.nih.gov/pubmed/29156831
http://dx.doi.org/10.18632/oncotarget.21418