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The role of Rak in the regulation of stability and function of BRCA1

BRCA1 is an important player in the DNA damage response signaling, and its deficiency results in genomic instability. A complete loss or significantly reduced BRCA1 protein expression is often found in sporadic breast cancer cases despite the absence of genetic or epigenetic aberrations, suggesting...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Lye, Ha, Geun-Hyoung, Campo, Loredana, Denning, Mitchell F., Patel, Tarun B., Osipo, Clodia, Lin, Shiaw-Yih, Breuer, Eun-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689726/
https://www.ncbi.nlm.nih.gov/pubmed/29156836
http://dx.doi.org/10.18632/oncotarget.5717