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Human Neural Stem Cell Biodistribution and Predicted Tumor Coverage by a Diffusible Therapeutic in a Mouse Glioma Model

Engineered neural stem cells (NSCs) intrinsically migrating to brain tumors offer a promising mechanism for local therapeutic delivery. However, difficulties in quantitative assessments of NSC migration and in estimates of tumor coverage by diffusible therapeutics have impeded development and refine...

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Detalles Bibliográficos
Autores principales: Barish, Michael E., Herrmann, Kelsey, Tang, Yang, Argalian Herculian, Siranush, Metz, Marianne, Aramburo, Soraya, Tirughana, Revathiswari, Gutova, Margarita, Annala, Alexander, Moats, Rex A., Goldstein, Leanne, Rockne, Russell C., Gutierrez, Jennifer, Brown, Christine E., Ghoda, Lucy, Aboody, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689763/
https://www.ncbi.nlm.nih.gov/pubmed/28481046
http://dx.doi.org/10.1002/sctm.16-0397