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Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease

Our understanding of mechanisms underlying progression from Mycobacterium tuberculosis infection to pulmonary tuberculosis disease in humans remains limited. To define such mechanisms, we followed M. tuberculosis-infected adolescents longitudinally. Blood samples from forty-four adolescents who ulti...

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Detalles Bibliográficos
Autores principales: Scriba, Thomas J., Penn-Nicholson, Adam, Shankar, Smitha, Hraha, Tom, Thompson, Ethan G., Sterling, David, Nemes, Elisa, Darboe, Fatoumatta, Suliman, Sara, Amon, Lynn M., Mahomed, Hassan, Erasmus, Mzwandile, Whatney, Wendy, Johnson, John L., Boom, W. Henry, Hatherill, Mark, Valvo, Joe, De Groote, Mary Ann, Ochsner, Urs A., Aderem, Alan, Hanekom, Willem A., Zak, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689825/
https://www.ncbi.nlm.nih.gov/pubmed/29145483
http://dx.doi.org/10.1371/journal.ppat.1006687