Estimating the probabilities of rare arrhythmic events in multiscale computational models of cardiac cells and tissue

Ectopic heartbeats can trigger reentrant arrhythmias, leading to ventricular fibrillation and sudden cardiac death. Such events have been attributed to perturbed Ca(2+) handling in cardiac myocytes leading to spontaneous Ca(2+) release and delayed afterdepolarizations (DADs). However, the ways in wh...

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Detalles Bibliográficos
Autores principales: Walker, Mark A., Gurev, Viatcheslav, Rice, John J., Greenstein, Joseph L., Winslow, Raimond L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689829/
https://www.ncbi.nlm.nih.gov/pubmed/29145393
http://dx.doi.org/10.1371/journal.pcbi.1005783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689829/
https://www.ncbi.nlm.nih.gov/pubmed/29145393
http://dx.doi.org/10.1371/journal.pcbi.1005783

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