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Estimating the probabilities of rare arrhythmic events in multiscale computational models of cardiac cells and tissue
Ectopic heartbeats can trigger reentrant arrhythmias, leading to ventricular fibrillation and sudden cardiac death. Such events have been attributed to perturbed Ca(2+) handling in cardiac myocytes leading to spontaneous Ca(2+) release and delayed afterdepolarizations (DADs). However, the ways in wh...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689829/ https://www.ncbi.nlm.nih.gov/pubmed/29145393 http://dx.doi.org/10.1371/journal.pcbi.1005783 |