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Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda2 protein

BACKGROUND: The reovirus λ2 protein catalyzes mRNA capping, that is, addition of a guanosine to the 5' end of each transcript in a 5'-to-5' orientation, as well as transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the N7 atom of the added guanosyl moiety and subseque...

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Detalles Bibliográficos
Autores principales: Bujnicki, Janusz M, Rychlewski, Leszek
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC56899/
https://www.ncbi.nlm.nih.gov/pubmed/11574057