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A PP2A-mediated feedback mechanism controls Ca(2+)-dependent NO synthesis under physiological oxygen
Intracellular O(2) is a key regulator of NO signaling, yet most in vitro studies are conducted in atmospheric O(2) levels, hyperoxic with respect to the physiologic milieu. We investigated NO signaling in endothelial cells cultured in physiologic (5%) O(2) and stimulated with histamine or shear stre...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690389/ https://www.ncbi.nlm.nih.gov/pubmed/28760745 http://dx.doi.org/10.1096/fj.201700211R |