Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway

Epigenetic mechanisms play important roles in the regulation of tumorigenesis, and hypoxia-induced epigenetic changes may be critical for the adaptation of cancer cells to the hypoxic microenvironment of solid tumors. Previously, we showed that loss-of-function of the hypoxia-regulated H3K9 methyltr...

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Detalles Bibliográficos
Autores principales: Ho, Jolene Caifeng, Abdullah, Lissa Nurrul, Pang, Qing You, Jha, Sudhakar, Chow, Edward Kai-Hua, Yang, Henry, Kato, Hiroyuki, Poellinger, Lorenz, Ueda, Jun, Lee, Kian Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690420/
https://www.ncbi.nlm.nih.gov/pubmed/29145444
http://dx.doi.org/10.1371/journal.pone.0188051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690420/
https://www.ncbi.nlm.nih.gov/pubmed/29145444
http://dx.doi.org/10.1371/journal.pone.0188051

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