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Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload

Stromal interaction molecule 1 (STIM1), an endo/sarcoplasmic reticulum Ca(2+) sensor, has been shown to control a Ca(2+)-dependent signal that promotes cardiac hypertrophy. However, whether STIM1 has adaptive role that helps to protect against cardiac overload stress remains unknown. We hypothesized...

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Detalles Bibliográficos
Autores principales: Ohba, Takayoshi, Watanabe, Hiroyuki, Murakami, Manabu, Iino, Kenji, Adachi, Takeshi, Baba, Yoshihiro, Kurosaki, Tomohiro, Ono, Kyoichi, Ito, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690472/
https://www.ncbi.nlm.nih.gov/pubmed/29145451
http://dx.doi.org/10.1371/journal.pone.0187950