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Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload
Stromal interaction molecule 1 (STIM1), an endo/sarcoplasmic reticulum Ca(2+) sensor, has been shown to control a Ca(2+)-dependent signal that promotes cardiac hypertrophy. However, whether STIM1 has adaptive role that helps to protect against cardiac overload stress remains unknown. We hypothesized...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690472/ https://www.ncbi.nlm.nih.gov/pubmed/29145451 http://dx.doi.org/10.1371/journal.pone.0187950 |