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Amiloride-enhanced gene transfection of octa-arginine functionalized calcium phosphate nanoparticles
Nanoparticles represent promising gene delivery systems in biomedicine to facilitate prolonged gene expression with low toxicity compared to viral vectors. Specifically, nanoparticles of calcium phosphate (nCaP), the main inorganic component of human bone, exhibit high biocompatibility and good biod...
Autores principales: | Vanegas Sáenz, Juan Ramón, Tenkumo, Taichi, Kamano, Yuya, Egusa, Hiroshi, Sasaki, Keiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690608/ https://www.ncbi.nlm.nih.gov/pubmed/29145481 http://dx.doi.org/10.1371/journal.pone.0188347 |
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