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Adenosine, lidocaine and Mg(2+) (ALM) fluid therapy attenuates systemic inflammation, platelet dysfunction and coagulopathy after non-compressible truncal hemorrhage

BACKGROUND: Systemic inflammation and coagulopathy are major drivers of injury progression following hemorrhagic trauma. Our aim was to examine the effect of small-volume 3% NaCl adenosine, lidocaine and Mg(2+) (ALM) bolus and 0.9% NaCl/ALM ‘drip’ on inflammation and coagulation in a rat model of he...

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Detalles Bibliográficos
Autores principales: Letson, Hayley, Dobson, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690633/
https://www.ncbi.nlm.nih.gov/pubmed/29145467
http://dx.doi.org/10.1371/journal.pone.0188144