Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1

Host genetic variation modifying HIV-1 acquisition risk can inform development of HIV-1 prevention strategies. However, associations between rare or intermediate-frequency variants and HIV-1 acquisition are not well studied. We tested for the association between variation in genic regions and extrem...

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Detalles Bibliográficos
Autores principales: Mackelprang, Romel D., Bamshad, Michael J., Chong, Jessica X., Hou, Xuanlin, Buckingham, Kati J., Shively, Kathryn, deBruyn, Guy, Mugo, Nelly R., Mullins, James I., McElrath, M. Juliana, Baeten, Jared M., Celum, Connie, Emond, Mary J., Lingappa, Jairam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690691/
https://www.ncbi.nlm.nih.gov/pubmed/29108000
http://dx.doi.org/10.1371/journal.ppat.1006703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690691/
https://www.ncbi.nlm.nih.gov/pubmed/29108000
http://dx.doi.org/10.1371/journal.ppat.1006703

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