Levosimendan protects human hepatocytes from ischemia-reperfusion injury

BACKGROUND: Ischemia-reperfusion injury (IRI) is a major challenge in liver transplantation. The mitochondrial pathway plays a pivotal role in hepatic IRI. Levosimendan, a calcium channel sensitizer, was shown to attenuate apoptosis after IRI in animal livers. The aim of this study was to investigat...

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Detalles Bibliográficos
Autores principales: Brunner, Stefanie N., Bogert, Nicolai V., Schnitzbauer, Andreas A., Juengel, Eva, Moritz, Anton, Werner, Isabella, Kornberger, Angela, Beiras-Fernandez, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690693/
https://www.ncbi.nlm.nih.gov/pubmed/29145424
http://dx.doi.org/10.1371/journal.pone.0187839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690693/
https://www.ncbi.nlm.nih.gov/pubmed/29145424
http://dx.doi.org/10.1371/journal.pone.0187839

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