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Levosimendan protects human hepatocytes from ischemia-reperfusion injury
BACKGROUND: Ischemia-reperfusion injury (IRI) is a major challenge in liver transplantation. The mitochondrial pathway plays a pivotal role in hepatic IRI. Levosimendan, a calcium channel sensitizer, was shown to attenuate apoptosis after IRI in animal livers. The aim of this study was to investigat...
Autores principales: | Brunner, Stefanie N., Bogert, Nicolai V., Schnitzbauer, Andreas A., Juengel, Eva, Moritz, Anton, Werner, Isabella, Kornberger, Angela, Beiras-Fernandez, Andres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690693/ https://www.ncbi.nlm.nih.gov/pubmed/29145424 http://dx.doi.org/10.1371/journal.pone.0187839 |
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