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Hippo, TGF-β, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection

Cytokine signaling is responsible for coordinating conserved epithelial regeneration and immune responses in the digestive tract. In the Drosophila midgut, Upd3 is a major cytokine, which is induced in enterocytes (EC) and enteroblasts (EB) upon oral infection, and initiates intestinal stem cell (IS...

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Detalles Bibliográficos
Autores principales: Houtz, Philip, Bonfini, Alessandro, Liu, Xi, Revah, Jonathan, Guillou, Aurélien, Poidevin, Mickael, Hens, Korneel, Huang, Hsin-Yi, Deplancke, Bart, Tsai, Yu-Chen, Buchon, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690694/
https://www.ncbi.nlm.nih.gov/pubmed/29108021
http://dx.doi.org/10.1371/journal.pgen.1007091